Missick is to portray Missy, a supposed version of Misty Knight and the female lead. Ali will portray Cornell “Cottonmouth” Stokes, a Harlem nightclub owner, who becomes an antagonist of Cage with his unsavory activities.
Missick and Ali join Mike Colter, who will be playing Luke Cage, and Alfre Woodard, who will be playing villain Black Mariah. Rosario Dawson will also reprise her role as Claire Temple from Daredevil.
Cheo Hodari Coker will serve as showrunner.
Luke Cage is set to be released on Netflix in 2016.